setting.ini definition, relationships, removal:

setting.ini is used by certain parasites to store essential settings of their components. These settings usually describe the malicious program's behavior, functionality and additional features.
The setting.ini file is installed and used by keylogger Sword.
Please note that the setting.ini file actually may be a fully legitimate part of the operating system or legitimate software. Often parasites use files with unsuspicious names, but malicious functionality. You should always carefully check the file before deleting it. It may not be related with malware, but can be required by your essential programs to work properly.