Well, what is the best?
I used to love Lavasoft Ad-aware SE (6), but it was natural because Ad-aware was the first antispyware program I had to use... it was free, simple and it did what it was supposed to do. As to version 2007, I think it's too resource-hungry. Interface is a little bit overcomplicated. Some people like it, some - don't. I belong to the latter.
Than, I tried Webroot SpySweeper. Pretty good application, though on my PC it loads too slow. Besides, it has less than 190,000 definitions of spyware, while ParetoLogic includes over 269,000 (as of now). Big difference to me.
I saw Panda IS 2007 in action as well. Perhaps it's a good all-in-one solution, but I would like it to provide more info on what it does in each and every detection case.
Several years ago it was not uncommon to have occasional pop-ups screaming about spyware infections and pleading to download the remedy. Now I don't see those pop-ups at all, perhaps because switched to FireFox
