Microsoft.VC80.ATL.manifest is a dangerous file, which can pose a serious harm to your computer and your privacy. It belongs to a parasite, which has an alternating payload. So, while relatively harmless pests may use Microsoft.VC80.ATL.manifest for degrading system performance, displaying commercial advertisements and performing other annoying activities, really dangerous parasites may use this file for damaging system, infecting files, installing dangerous software and violating people's privacy. According to security experts, Microsoft.VC80.ATL.manifest is installed and used by PC Privacy Defender. DO NOT open this file!
However, sometimes the presence of this file does not indicate that computer is infected. Although such cases are very rare, you should thoroughly examine Microsoft.VC80.ATL.manifest before deleting or leaving it in the system. For that we recommend using RegCure Pro.